Epigenetic activation during T helper 17 cell differentiation is mediated by Tripartite motif containing 28

Epigenetic regulation is important for T-cell fate decision. Although STAT3 is known to initiate Th17 differentiation program, the downstream mechanism is unclear. Here we show that Tripartite motif containing 28 (Trim28) expression in Th17 cells is required for Th17-mediated cytokine production and...

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Detalles Bibliográficos
Autores principales: Jiang, Yu, Liu, Ying, Lu, Huiping, Sun, Shao-Cong, Jin, Wei, Wang, Xiaohu, Dong, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897371/
https://www.ncbi.nlm.nih.gov/pubmed/29651155
http://dx.doi.org/10.1038/s41467-018-03852-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897371/
https://www.ncbi.nlm.nih.gov/pubmed/29651155
http://dx.doi.org/10.1038/s41467-018-03852-2

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