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A mega-analysis of expression quantitative trait loci (eQTL) provides insight into the regulatory architecture of gene expression variation in liver

Genome-wide association studies (GWAS) have identified numerous genetic variants in the human genome associated with diseases and traits. Nevertheless, for most loci the causative variant is still unknown. Expression quantitative trait loci (eQTL) in disease relevant tissues is an excellent approach...

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Detalles Bibliográficos
Autores principales: Strunz, Tobias, Grassmann, Felix, Gayán, Javier, Nahkuri, Satu, Souza-Costa, Debora, Maugeais, Cyrille, Fauser, Sascha, Nogoceke, Everson, Weber, Bernhard H. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897392/
https://www.ncbi.nlm.nih.gov/pubmed/29650998
http://dx.doi.org/10.1038/s41598-018-24219-z