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Role of Kisspeptin and Neurokinin B in Puberty in Female Non-Human Primates

In human patients, loss-of-function mutations in the genes encoding kisspeptin (KISS1) and neurokinin B (NKB) and their receptors (KISS1R and NK3R, respectively) result in an abnormal timing of puberty or the absence of puberty. To understand the neuroendocrine mechanism of puberty, we investigated...

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Detalles Bibliográficos
Autores principales: Terasawa, Ei, Garcia, James P., Seminara, Stephanie B., Keen, Kim L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897421/
https://www.ncbi.nlm.nih.gov/pubmed/29681889
http://dx.doi.org/10.3389/fendo.2018.00148