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Inhibitors of protein translocation across membranes of the secretory pathway: novel antimicrobial and anticancer agents

Proteins routed to the secretory pathway start their journey by being transported across biological membranes, such as the endoplasmic reticulum. The essential nature of this protein translocation process has led to the evolution of several factors that specifically target the translocon and block t...

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Detalles Bibliográficos
Autores principales: Van Puyenbroeck, Victor, Vermeire, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897483/
https://www.ncbi.nlm.nih.gov/pubmed/29305616
http://dx.doi.org/10.1007/s00018-017-2743-2