High Dietary Iron Supplement Induces the Nigrostriatal Dopaminergic Neurons Lesion in Transgenic Mice Expressing Mutant A53T Human Alpha-Synuclein

Both alpha-synuclein aggregation and iron deposits are neuropathological hallmarks of Parkinson’s disease (PD). We are particularly interested in whether iron could synergize with alpha-synuclein pathology in vivo, especially in the nigrostriatal system. In the present study, we reported transgenic...

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Detalles Bibliográficos
Autores principales: Jia, Fengju, Song, Ning, Wang, Weiwei, Du, Xixun, Chi, Yajing, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897504/
https://www.ncbi.nlm.nih.gov/pubmed/29681846
http://dx.doi.org/10.3389/fnagi.2018.00097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897504/
https://www.ncbi.nlm.nih.gov/pubmed/29681846
http://dx.doi.org/10.3389/fnagi.2018.00097

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