Surface Expression, Function, and Pharmacology of Disease-Associated Mutations in the Membrane Domain of the Human GluN2B Subunit

N-methyl-D-aspartate receptors (NMDARs), glutamate-gated ion channels, mediate signaling at the majority of excitatory synapses in the nervous system. Recent sequencing data for neurological and psychiatric patients have indicated numerous mutations in genes encoding for NMDAR subunits. Here, we pre...

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Detalles Bibliográficos
Autores principales: Vyklicky, Vojtech, Krausova, Barbora, Cerny, Jiri, Ladislav, Marek, Smejkalova, Tereza, Kysilov, Bohdan, Korinek, Miloslav, Danacikova, Sarka, Horak, Martin, Chodounska, Hana, Kudova, Eva, Vyklicky, Ladislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897658/
https://www.ncbi.nlm.nih.gov/pubmed/29681796
http://dx.doi.org/10.3389/fnmol.2018.00110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897658/
https://www.ncbi.nlm.nih.gov/pubmed/29681796
http://dx.doi.org/10.3389/fnmol.2018.00110

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