Epithelial and stromal circadian clocks are inversely regulated by their mechano-matrix environment

The circadian clock is an autonomous molecular feedback loop inside almost every cell in the body. We have shown that the mammary epithelial circadian clock is regulated by the cellular microenvironment. Moreover, a stiff extracellular matrix dampens the oscillations of the epithelial molecular cloc...

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Detalles Bibliográficos
Autores principales: Williams, Jack, Yang, Nan, Wood, Amber, Zindy, Egor, Meng, Qing-Jun, Streuli, Charles H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897718/
https://www.ncbi.nlm.nih.gov/pubmed/29361531
http://dx.doi.org/10.1242/jcs.208223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897718/
https://www.ncbi.nlm.nih.gov/pubmed/29361531
http://dx.doi.org/10.1242/jcs.208223

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