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Epithelial and stromal circadian clocks are inversely regulated by their mechano-matrix environment
The circadian clock is an autonomous molecular feedback loop inside almost every cell in the body. We have shown that the mammary epithelial circadian clock is regulated by the cellular microenvironment. Moreover, a stiff extracellular matrix dampens the oscillations of the epithelial molecular cloc...
Autores principales: | Williams, Jack, Yang, Nan, Wood, Amber, Zindy, Egor, Meng, Qing-Jun, Streuli, Charles H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897718/ https://www.ncbi.nlm.nih.gov/pubmed/29361531 http://dx.doi.org/10.1242/jcs.208223 |
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