Mek1(Y130C) mice recapitulate aspects of human cardio-facio-cutaneous syndrome

The RAS/MAPK signaling pathway is one of the most investigated pathways, owing to its established role in numerous cellular processes and implication in cancer. Germline mutations in genes encoding members of the RAS/MAPK pathway also cause severe developmental syndromes collectively known as RASopa...

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Detalles Bibliográficos
Autores principales: Aoidi, Rifdat, Houde, Nicolas, Landry-Truchon, Kim, Holter, Michael, Jacquet, Kevin, Charron, Louis, Krishnaswami, Suguna Rani, Yu, Benjamin D., Rauen, Katherine A., Bisson, Nicolas, Newbern, Jason, Charron, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897723/
https://www.ncbi.nlm.nih.gov/pubmed/29590634
http://dx.doi.org/10.1242/dmm.031278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897723/
https://www.ncbi.nlm.nih.gov/pubmed/29590634
http://dx.doi.org/10.1242/dmm.031278

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