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Identification of protective postexposure mycobacterial vaccine antigens using an immunosuppression-based reactivation model in the zebrafish

Roughly one third of the human population carries a latent Mycobacterium tuberculosis infection, with a 5-10% lifetime risk of reactivation to active tuberculosis and further spreading the disease. The mechanisms leading to the reactivation of a latent Mycobacterium tuberculosis infection are insuff...

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Detalles Bibliográficos
Autores principales: Myllymäki, Henna, Niskanen, Mirja, Luukinen, Hanna, Parikka, Mataleena, Rämet, Mika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897733/
https://www.ncbi.nlm.nih.gov/pubmed/29590635
http://dx.doi.org/10.1242/dmm.033175