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Identification of protective postexposure mycobacterial vaccine antigens using an immunosuppression-based reactivation model in the zebrafish
Roughly one third of the human population carries a latent Mycobacterium tuberculosis infection, with a 5-10% lifetime risk of reactivation to active tuberculosis and further spreading the disease. The mechanisms leading to the reactivation of a latent Mycobacterium tuberculosis infection are insuff...
Autores principales: | Myllymäki, Henna, Niskanen, Mirja, Luukinen, Hanna, Parikka, Mataleena, Rämet, Mika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897733/ https://www.ncbi.nlm.nih.gov/pubmed/29590635 http://dx.doi.org/10.1242/dmm.033175 |
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