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Chemical synthesis of membrane proteins: a model study on the influenza virus B proton channel

In the present study we have developed and optimized a robust strategy for the synthesis of highly hydrophobic peptides, especially membrane proteins, exemplarily using the influenza B M2 proton channel (BM2(1–51)). This strategy is based on the native chemical ligation of two fragments, where the t...

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Detalles Bibliográficos
Autores principales: Baumruck, A. C., Tietze, D., Steinacker, L. K., Tietze, A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897842/
https://www.ncbi.nlm.nih.gov/pubmed/29719709
http://dx.doi.org/10.1039/c8sc00004b