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Overexpression of a type III PKS gene affording novel violapyrones with enhanced anti-influenza A virus activity

BACKGROUND: Type III polyketide synthases (PKSs) are simple homodimer ketosynthases that distribute across plants, fungi, and bacteria, catalyzing formation of pyrone- and resorcinol-types aromatic polyketides with various bioactivities. The broad substrate promiscuity displayed by type III PKSs mak...

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Detalles Bibliográficos
Autores principales: Hou, Lukuan, Huang, Huiming, Li, Huayue, Wang, Shuyao, Ju, Jianhua, Li, Wenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898002/
https://www.ncbi.nlm.nih.gov/pubmed/29650021
http://dx.doi.org/10.1186/s12934-018-0908-9