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Overexpression of a type III PKS gene affording novel violapyrones with enhanced anti-influenza A virus activity
BACKGROUND: Type III polyketide synthases (PKSs) are simple homodimer ketosynthases that distribute across plants, fungi, and bacteria, catalyzing formation of pyrone- and resorcinol-types aromatic polyketides with various bioactivities. The broad substrate promiscuity displayed by type III PKSs mak...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898002/ https://www.ncbi.nlm.nih.gov/pubmed/29650021 http://dx.doi.org/10.1186/s12934-018-0908-9 |