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Histone H3K9 and H4 Acetylations and Transcription Facilitate the Initial CENP-A(HCP−3) Deposition and De Novo Centromere Establishment in Caenorhabditis elegans Artificial Chromosomes
BACKGROUND: The centromere is the specialized chromatin region that directs chromosome segregation. The kinetochore assembles on the centromere, attaching chromosomes to microtubules in mitosis. The centromere position is usually maintained through cell cycles and generations. However, new centromer...
Autores principales: | Zhu, Jing, Cheng, Kevin Chi Lok, Yuen, Karen Wing Yee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898018/ https://www.ncbi.nlm.nih.gov/pubmed/29653589 http://dx.doi.org/10.1186/s13072-018-0185-1 |
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