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Streamlined histone-based fluorescence lifetime imaging microscopy (FLIM) for studying chromatin organisation
Changes in chromatin structure are key determinants of genomic responses. Thus, methods that enable such measurements are instrumental for investigating genome regulation and function. Here, we report further developments and validation of a streamlined method of histone-based fluorescence lifetime...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898265/ https://www.ncbi.nlm.nih.gov/pubmed/29535103 http://dx.doi.org/10.1242/bio.031476 |