A Simple, Rapid, and Quantitative Assay to Measure Repair of DNA-protein Crosslinks on Plasmids Transfected into Mammalian Cells

The purpose of this method is to provide a flexible, rapid, and quantitative technique to examine the kinetics of DNA-protein crosslink (DPC) repair in mammalian cell lines. Rather than globally assaying removal of xenobiotic-induced or spontaneous chromosomal DPC removal, this assay examines the re...

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Detalles Bibliográficos
Autores principales: Chesner, Lisa N., Campbell, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2018
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898435/
https://www.ncbi.nlm.nih.gov/pubmed/29553515
http://dx.doi.org/10.3791/57413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898435/
https://www.ncbi.nlm.nih.gov/pubmed/29553515
http://dx.doi.org/10.3791/57413

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