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Interval estimation of the overall treatment effect in a meta-analysis of a few small studies with zero events

When a meta-analysis consists of a few small trials that report zero events, accounting for heterogeneity in the (interval) estimation of the overall effect is challenging. Typically, we predefine meta-analytical methods to be employed. In practice, data poses restrictions that lead to deviations fr...

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Detalles Bibliográficos
Autores principales: Pateras, Konstantinos, Nikolakopoulos, Stavros, Mavridis, Dimitris, Roes, Kit C.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898531/
https://www.ncbi.nlm.nih.gov/pubmed/29696231
http://dx.doi.org/10.1016/j.conctc.2017.11.012