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Sensitivity of adaptive enrichment trial designs to accrual rates, time to outcome measurement, and prognostic variables
Adaptive enrichment designs involve rules for restricting enrollment to a subset of the population during the course of an ongoing trial. This can be used to target those who benefit from the experimental treatment. Trial characteristics such as the accrual rate and the prognostic value of baseline...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898543/ https://www.ncbi.nlm.nih.gov/pubmed/29696195 http://dx.doi.org/10.1016/j.conctc.2017.08.003 |