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Bayesian adaptive clinical trials of combination treatments
Randomized clinical trials (RCT) increasingly investigate combination therapies. Strong biological rationale or early clinical evidence commonly suggest that the effect of the combination treatment is importantly greater than the maximum effect of any of the individual treatments. While these relati...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898557/ https://www.ncbi.nlm.nih.gov/pubmed/29696213 http://dx.doi.org/10.1016/j.conctc.2017.11.001 |