Decision on performing interim analysis for comparative clinical trials

In randomized-controlled trials, interim analyses are often planned for possible early trial termination to claim superiority or futility of a new therapy. While unblinding is necessary to conduct the formal interim analysis in blinded studies, blinded data also have information about the potential...

Descripción completa

Detalles Bibliográficos
Autores principales: Pak, Kyongsun, Jacobus, Susanna, Uno, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898570/
https://www.ncbi.nlm.nih.gov/pubmed/29696190
http://dx.doi.org/10.1016/j.conctc.2017.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898570/
https://www.ncbi.nlm.nih.gov/pubmed/29696190
http://dx.doi.org/10.1016/j.conctc.2017.08.001

Ejemplares similares