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Crocin induces autophagic apoptosis in hepatocellular carcinoma by inhibiting Akt/mTOR activity
BACKGROUND: Autophagy induction is a common mechanism for antitumor chemicals in induction of cancer cell death. However, the role of autophagy in crocin-induced apoptosis is barely studied in hepatocellular carcinoma (HCC). MATERIALS AND METHODS: The influence of crocin on growth, apoptosis, and au...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898595/ https://www.ncbi.nlm.nih.gov/pubmed/29670377 http://dx.doi.org/10.2147/OTT.S154586 |