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Involvement of pro-inflammation signal pathway in inhibitory effects of rapamycin on oxaliplatin-induced neuropathic pain

BACKGROUND: Oxaliplatin is a third-generation chemotherapeutic agent that is commonly used to treat metastatic digestive tumors; however, one of the main limiting complications of oxaliplatin is painful peripheral neuropathy. The purpose of this study was to examine the underlying mechanisms by whic...

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Detalles Bibliográficos
Autores principales: Duan, Zongsheng, Su, Zhenbo, Wang, Hushan, Pang, Xiaochuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898663/
https://www.ncbi.nlm.nih.gov/pubmed/29587559
http://dx.doi.org/10.1177/1744806918769426