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The Effect of Tissue Preparation and Donor Age on Striatal Graft Morphology in the Mouse

Huntington's disease (HD) is a progressive neurodegenerative disease in which striatal medium spiny neurons (MSNs) are lost. Neuronal replacement therapies aim to replace MSNs through striatal transplantation of donor MSN progenitors, which successfully improve HD-like deficits in rat HD models...

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Detalles Bibliográficos
Autores principales: Harrison, David J., Roberton, Victoria H., Vinh, Ngoc-Nga, Brooks, Simon P., Dunnett, Stephen B., Rosser, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898691/
https://www.ncbi.nlm.nih.gov/pubmed/29637815
http://dx.doi.org/10.1177/0963689717744788