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Immunogenicity and safety of three consecutive production lots of the non replicating smallpox vaccine MVA: A randomised, double blind, placebo controlled phase III trial

BACKGROUND: Modified Vaccinia Ankara (MVA) is a live, viral vaccine under advanced development as a non-replicating smallpox vaccine. A randomised, double-blind, placebo-controlled phase III clinical trial was conducted to demonstrate the humoral immunogenic equivalence of three consecutively manufa...

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Detalles Bibliográficos
Autores principales: Overton, Edgar Turner, Lawrence, Steven J., Wagner, Eva, Nopora, Katrin, Rösch, Siegfried, Young, Philip, Schmidt, Darja, Kreusel, Christian, De Carli, Sonja, Meyer, Thomas P., Weidenthaler, Heinz, Samy, Nathaly, Chaplin, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898760/
https://www.ncbi.nlm.nih.gov/pubmed/29652929
http://dx.doi.org/10.1371/journal.pone.0195897