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Early postnatal soluble FGFR3 therapy prevents the atypical development of obesity in achondroplasia

BACKGROUND: Achondroplasia is a rare genetic disease is characterized by abnormal bone development and early obesity. While the bone aspect of the disease has been thoroughly studied, early obesity affecting approximately 50% of them during childhood has been somewhat neglected. It nevertheless repr...

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Detalles Bibliográficos
Autores principales: Saint-Laurent, Celine, Garcia, Stephanie, Sarrazy, Vincent, Dumas, Karine, Authier, Florence, Sore, Sophie, Tran, Albert, Gual, Philippe, Gennero, Isabelle, Salles, Jean-Pierre, Gouze, Elvire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898762/
https://www.ncbi.nlm.nih.gov/pubmed/29652901
http://dx.doi.org/10.1371/journal.pone.0195876