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Computational analysis of the oscillatory behavior at the translation level induced by mRNA levels oscillations due to finite intracellular resources

Recent studies have demonstrated how the competition for the finite pool of available gene expression factors has important effect on fundamental gene expression aspects. In this study, based on a whole-cell model simulation of translation in S. cerevisiae, we evaluate for the first time the expecte...

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Detalles Bibliográficos
Autores principales: Zarai, Yoram, Tuller, Tamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898785/
https://www.ncbi.nlm.nih.gov/pubmed/29614119
http://dx.doi.org/10.1371/journal.pcbi.1006055