Impaired Na(+)−K(+)-ATPase signaling in renal proximal tubule contributes to hyperuricemia-induced renal tubular injury

Hyperuricemia contributes to renal inflammation. We aimed to investigate the role of Na(+)–K(+)–ATPase (NKA) in hyperuricemia-induced renal tubular injury. Human primary proximal tubular epithelial cells (PTECs) were incubated with uric acid (UA) at increasing doses or for increasing lengths of time...

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Detalles Bibliográficos
Autores principales: Xiao, Jing, Zhang, Xiaoli, Fu, Chensheng, Yang, Qingmei, Xie, Ying, Zhang, Zhenxing, Ye, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898891/
https://www.ncbi.nlm.nih.gov/pubmed/29497172
http://dx.doi.org/10.1038/emm.2017.287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898891/
https://www.ncbi.nlm.nih.gov/pubmed/29497172
http://dx.doi.org/10.1038/emm.2017.287

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