Impaired Na(+)−K(+)-ATPase signaling in renal proximal tubule contributes to hyperuricemia-induced renal tubular injury

Hyperuricemia contributes to renal inflammation. We aimed to investigate the role of Na(+)–K(+)–ATPase (NKA) in hyperuricemia-induced renal tubular injury. Human primary proximal tubular epithelial cells (PTECs) were incubated with uric acid (UA) at increasing doses or for increasing lengths of time...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiao, Jing, Zhang, Xiaoli, Fu, Chensheng, Yang, Qingmei, Xie, Ying, Zhang, Zhenxing, Ye, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898891/
https://www.ncbi.nlm.nih.gov/pubmed/29497172
http://dx.doi.org/10.1038/emm.2017.287

Ejemplares similares

Ejemplares similares