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Evaluation of several methodological challenges in circulating miRNA qPCR studies in patients with head and neck cancer

Circulating microRNAs (ci-miRNAs) in blood have emerged as promising diagnostic, prognostic and predictive biomarkers in cancer. Many clinical studies currently incorporate studies that assess ci-miRNAs. Validation of the clinical significance of candidate biomarker miRNAs has proven to be difficult...

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Detalles Bibliográficos
Autores principales: Poel, Dennis, Buffart, Tineke E, Oosterling-Jansen, Jolanda, Verheul, Henk MW, Voortman, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898892/
https://www.ncbi.nlm.nih.gov/pubmed/29520111
http://dx.doi.org/10.1038/emm.2017.288