Capsaicin upregulates HDAC2 via TRPV1 and impairs neuronal maturation in mice

Transient receptor potential vanilloid 1 (TRPV1) affects mood and neuroplasticity in the brain, where its role is poorly understood. In the present study we investigated whether capsaicin (8-methyl-N-vanillyl-trans-6-nonenamide), an agonist of TRPV1, induced chromatin remodeling and thereby altered...

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Detalles Bibliográficos
Autores principales: Wang, Sung Eun, Ko, Seung Yeon, Kim, Yong-Seok, Jo, Sungsin, Lee, Seung Hoon, Jung, Sung Jun, Son, Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898893/
https://www.ncbi.nlm.nih.gov/pubmed/29520110
http://dx.doi.org/10.1038/emm.2017.289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898893/
https://www.ncbi.nlm.nih.gov/pubmed/29520110
http://dx.doi.org/10.1038/emm.2017.289

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