Intrahippocampal injection of a lentiviral vector expressing neurogranin enhances cognitive function in 5XFAD mice

Progressive cognitive declines are the main clinical symptoms of Alzheimer’s disease (AD). Cognitive impairment in AD is directly correlated with amyloid beta (Aβ)-mediated synaptic deficits. It is known that upregulation of neurogranin (Ng), a postsynaptic protein, contributes to the enhancement of...

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Detalles Bibliográficos
Autores principales: Jeon, Seong Gak, Kang, Moonkyung, Kim, Yeon-Soo, Kim, Dong-Hyun, Nam, Dong Woo, Song, Eun Ji, Mook-Jung, Inhee, Moon, Minho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898899/
https://www.ncbi.nlm.nih.gov/pubmed/29568074
http://dx.doi.org/10.1038/emm.2017.302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898899/
https://www.ncbi.nlm.nih.gov/pubmed/29568074
http://dx.doi.org/10.1038/emm.2017.302

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