Cargando…

Toxoplasma gondii GRA8 induces ATP5A1–SIRT3-mediated mitochondrial metabolic resuscitation: a potential therapy for sepsis

The intracellular parasite Toxoplasma gondii has unique dense granule antigens (GRAs) that are crucial for host infection. Emerging evidence suggests that GRA8 of T. gondii is a promising serodiagnostic marker in toxoplasmosis. However, little is known about the intracellular regulatory mechanisms i...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Ye-Ram, Kim, Jae-Sung, Yun, Jin-Seung, Kim, Sojin, Kim, Sun Young, Jang, Kiseok, Yang, Chul-Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898902/
https://www.ncbi.nlm.nih.gov/pubmed/29869623
http://dx.doi.org/10.1038/emm.2017.308