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Normal mitochondrial function in Saccharomyces cerevisiae has become dependent on inefficient splicing

Self-splicing introns are mobile elements that have invaded a number of highly conserved genes in prokaryotic and organellar genomes. Here, we show that deletion of these selfish elements from the Saccharomyces cerevisiae mitochondrial genome is stressful to the host. A strain without mitochondrial...

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Detalles Bibliográficos
Autores principales: Rudan, Marina, Bou Dib, Peter, Musa, Marina, Kanunnikau, Matea, Sobočanec, Sandra, Rueda, David, Warnecke, Tobias, Kriško, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898908/
https://www.ncbi.nlm.nih.gov/pubmed/29570052
http://dx.doi.org/10.7554/eLife.35330