Differential 3’ processing of specific transcripts expands regulatory and protein diversity across neuronal cell types

Alternative polyadenylation (APA) regulates mRNA translation, stability, and protein localization. However, it is unclear to what extent APA regulates these processes uniquely in specific cell types. Using a new technique, cTag-PAPERCLIP, we discovered significant differences in APA between the prin...

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Detalles Bibliográficos
Autores principales: Jereb, Saša, Hwang, Hun-Way, Van Otterloo, Eric, Govek, Eve-Ellen, Fak, John J, Yuan, Yuan, Hatten, Mary E, Darnell, Robert B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898910/
https://www.ncbi.nlm.nih.gov/pubmed/29578408
http://dx.doi.org/10.7554/eLife.34042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898910/
https://www.ncbi.nlm.nih.gov/pubmed/29578408
http://dx.doi.org/10.7554/eLife.34042

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