Identification of Collateral Sensitivity to Dihydroorotate Dehydrogenase Inhibitors in Plasmodium falciparum

[Image: see text] Drug resistance has been reported for every antimalarial in use highlighting the need for new strategies to protect the efficacy of therapeutics in development. We have previously shown that resistance can be suppressed with a population biology trap: by identifying situations wher...

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Detalles Bibliográficos
Autores principales: Ross, Leila Saxby, Lafuente-Monasterio, Maria José, Sakata-Kato, Tomoyo, Mandt, Rebecca E. K., Gamo, Francisco Javier, Wirth, Dyann F., Lukens, Amanda K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899019/
https://www.ncbi.nlm.nih.gov/pubmed/29336544
http://dx.doi.org/10.1021/acsinfecdis.7b00217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899019/
https://www.ncbi.nlm.nih.gov/pubmed/29336544
http://dx.doi.org/10.1021/acsinfecdis.7b00217

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