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Hedgehog Interacting Protein Promotes Fibrosis and Apoptosis in Glomerular Endothelial Cells in Murine Diabetes

We investigated whether renal hedgehog interacting protein (Hhip) expression contributes to the progression of diabetic nephropathy (DN) and studied its related mechanism(s) in vivo and in vitro. Here, we show that Hhip expression is highly elevated in glomerular endothelial cells of adult type 1 di...

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Detalles Bibliográficos
Autores principales: Zhao, Xin-Ping, Chang, Shiao-Ying, Liao, Min-Chun, Lo, Chao-Sheng, Chenier, Isabelle, Luo, Hongyu, Chiasson, Jean-Louis, Ingelfinger, Julie R., Chan, John S. D., Zhang, Shao-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899163/
https://www.ncbi.nlm.nih.gov/pubmed/29654303
http://dx.doi.org/10.1038/s41598-018-24220-6