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Carboxythiazole is a key microbial nutrient currency and critical component of thiamin biosynthesis

Almost all cells require thiamin, vitamin B1 (B1), which is synthesized via the coupling of thiazole and pyrimidine precursors. Here we demonstrate that 5-(2-hydroxyethyl)-4-methyl-1,3-thiazole-2-carboxylic acid (cHET) is a useful in vivo B1 precursor for representatives of ubiquitous marine picoeuk...

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Detalles Bibliográficos
Autores principales: Paerl, Ryan W., Bertrand, Erin M., Rowland, Elden, Schatt, Phillippe, Mehiri, Mohamed, Niehaus, Thomas D., Hanson, Andrew D., Riemann, Lasse, Bouget, Francois-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899164/
https://www.ncbi.nlm.nih.gov/pubmed/29654239
http://dx.doi.org/10.1038/s41598-018-24321-2