Loss of caveolin-3-dependent regulation of I(Ca) in rat ventricular myocytes in heart failure

β(2)-Adrenoceptors and L-type Ca(2+) current (I(Ca)) redistribute from the t-tubules to the surface membrane of ventricular myocytes from failing hearts. The present study investigated the role of changes in caveolin-3 and PKA signaling, both of which have previously been implicated in this redistri...

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Detalles Bibliográficos
Autores principales: Bryant, Simon M., Kong, Cherrie H. T., Cannell, Mark B., Orchard, Clive H., James, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899261/
https://www.ncbi.nlm.nih.gov/pubmed/29101175
http://dx.doi.org/10.1152/ajpheart.00458.2017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899261/
https://www.ncbi.nlm.nih.gov/pubmed/29101175
http://dx.doi.org/10.1152/ajpheart.00458.2017

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