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Loss of caveolin-3-dependent regulation of I(Ca) in rat ventricular myocytes in heart failure

β(2)-Adrenoceptors and L-type Ca(2+) current (I(Ca)) redistribute from the t-tubules to the surface membrane of ventricular myocytes from failing hearts. The present study investigated the role of changes in caveolin-3 and PKA signaling, both of which have previously been implicated in this redistri...

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Detalles Bibliográficos
Autores principales:	Bryant, Simon M., Kong, Cherrie H. T., Cannell, Mark B., Orchard, Clive H., James, Andrew F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899261/ https://www.ncbi.nlm.nih.gov/pubmed/29101175 http://dx.doi.org/10.1152/ajpheart.00458.2017

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