Optimization of the EC26-2A4 Epitope in the gp41 Membrane Proximal External Region Targeted by Neutralizing Antibodies from an Elite Controller

The analysis of patient derived HIV neutralizing antibodies (nAbs) and their target epitopes in the viral envelope (Env) protein provides important basic information for vaccine design. In this study we optimized an epitope, EC26-2A4, that is targeted by neutralizing antibodies from an elite control...

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Detalles Bibliográficos
Autores principales: Ringel, Oliver, Müller, Karsten, Koch, Joachim, Brill, Boris, Wolf, Timo, Stephan, Christoph, Vieillard, Vincent, Debré, Patrice, Dietrich, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Vaccines
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899297/
https://www.ncbi.nlm.nih.gov/pubmed/29262692
http://dx.doi.org/10.1089/aid.2017.0250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899297/
https://www.ncbi.nlm.nih.gov/pubmed/29262692
http://dx.doi.org/10.1089/aid.2017.0250

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