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Optimization of the EC26-2A4 Epitope in the gp41 Membrane Proximal External Region Targeted by Neutralizing Antibodies from an Elite Controller
The analysis of patient derived HIV neutralizing antibodies (nAbs) and their target epitopes in the viral envelope (Env) protein provides important basic information for vaccine design. In this study we optimized an epitope, EC26-2A4, that is targeted by neutralizing antibodies from an elite control...
Autores principales: | Ringel, Oliver, Müller, Karsten, Koch, Joachim, Brill, Boris, Wolf, Timo, Stephan, Christoph, Vieillard, Vincent, Debré, Patrice, Dietrich, Ursula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899297/ https://www.ncbi.nlm.nih.gov/pubmed/29262692 http://dx.doi.org/10.1089/aid.2017.0250 |
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