Cargando…

Abnormal visual gain control and excitotoxicity in early-onset Parkinson’s disease Drosophila models

The excitotoxic theory of Parkinson’s disease (PD) hypothesizes that a pathophysiological degeneration of dopaminergic neurons stems from neural hyperactivity at early stages of disease, leading to mitochondrial stress and cell death. Recent research has harnessed the visual system of Drosophila PD...

Descripción completa

Detalles Bibliográficos
Autores principales: Himmelberg, Marc M., West, Ryan J. H., Elliott, Christopher J. H., Wade, Alex R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899316/
https://www.ncbi.nlm.nih.gov/pubmed/29142100
http://dx.doi.org/10.1152/jn.00681.2017