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Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells

BACKGROUND: Dysregulation of microRNA (miRNA) expression is associated with hallmarks of aggressive tumor phenotypes, e.g., enhanced cell growth, proliferation, invasion, and anchorage independent growth in prostate cancer (PCa). METHODS: Serum-based miRNA profiling involved 15 men diagnosed with no...

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Detalles Bibliográficos
Autores principales: Jones, Dominique Z., Schmidt, M. Lee, Suman, Suman, Hobbing, Katharine R., Barve, Shirish S., Gobejishvili, Leila, Brock, Guy, Klinge, Carolyn M., Rai, Shesh N., Park, Jong, Clark, Geoffrey J., Agarwal, Rajesh, Kidd, LaCreis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899400/
https://www.ncbi.nlm.nih.gov/pubmed/29653561
http://dx.doi.org/10.1186/s12885-018-4258-0