Loss of TDP43 inhibits progression of triple-negative breast cancer in coordination with SRSF3

Aberrant alternative splicing has been highlighted as a potential hallmark of cancer. Here, we identify TDP43 (TAR DNA-binding protein 43) as an important splicing regulator responsible for the unique splicing profile in triple-negative breast cancer (TNBC). Clinical data demonstrate that TDP43 is h...

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Detalles Bibliográficos
Autores principales: Ke, Hao, Zhao, Limin, Zhang, Honglei, Feng, Xu, Xu, Haibo, Hao, Junjun, Wang, Shaowei, Yang, Qin, Zou, Li, Su, Xiaosan, Wang, Liqiong, Wu, Chunlian, Wang, Yang, Nie, Jianyun, Jiao, Baowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899436/
https://www.ncbi.nlm.nih.gov/pubmed/29581274
http://dx.doi.org/10.1073/pnas.1714573115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899436/
https://www.ncbi.nlm.nih.gov/pubmed/29581274
http://dx.doi.org/10.1073/pnas.1714573115

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