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RNA-mediated gene regulation is less evolvable than transcriptional regulation

Much of gene regulation is carried out by proteins that bind DNA or RNA molecules at specific sequences. One class of such proteins is transcription factors, which bind short DNA sequences to regulate transcription. Another class is RNA binding proteins, which bind short RNA sequences to regulate RN...

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Detalles Bibliográficos
Autores principales: Payne, Joshua L., Khalid, Fahad, Wagner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899451/
https://www.ncbi.nlm.nih.gov/pubmed/29581298
http://dx.doi.org/10.1073/pnas.1719138115