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Population Snapshots Predict Early Hematopoietic and Erythroid Hierarchies

Red cell formation begins with the differentiation of multipotent hematopoietic progenitors. Reconstructing the steps of differentiation represents a stereotypical challenge in stem cell biology. Combining single-cell transcriptomics, fate assays, and theory for predicting fate from population snaps...

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Detalles Bibliográficos
Autores principales: Tusi, Betsabeh Khoramian, Wolock, Samuel L., Weinreb, Caleb, Hwang, Yung, Hidalgo, Daniel, Zilionis, Rapolas, Waisman, Ari, Huh, Jun R., Klein, Allon M., Socolovsky, Merav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899604/
https://www.ncbi.nlm.nih.gov/pubmed/29466336
http://dx.doi.org/10.1038/nature25741