An exploratory clinical study of p38α kinase inhibition in Alzheimer's disease

OBJECTIVE: The aim of this study was to preliminarily evaluate an oral small molecule p38α kinase inhibitor in patients with early Alzheimer's disease (AD) for the effects on brain amyloid plaque load and episodic memory function, and to establish pharmacokinetic–pharmacodynamics correlations i...

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Detalles Bibliográficos
Autores principales: Scheltens, Philip, Prins, Niels, Lammertsma, Adriaan, Yaqub, Maqsood, Gouw, Alida, Wink, Alle Meije, Chu, Hui‐May, van Berckel, Bart N. M., Alam, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899915/
https://www.ncbi.nlm.nih.gov/pubmed/29687023
http://dx.doi.org/10.1002/acn3.549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899915/
https://www.ncbi.nlm.nih.gov/pubmed/29687023
http://dx.doi.org/10.1002/acn3.549

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