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Fosl1 overexpression directly activates trophoblast-specific gene expression programs in embryonic stem cells

During early development in placental mammals, proper trophoblast lineage development is essential for implantation and placentation. Defects in this lineage can cause early pregnancy failures and other pregnancy disorders. However, transcription factors controlling trophoblast development remain po...

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Detalles Bibliográficos
Autores principales: Lee, Bum-Kyu, Uprety, Nadima, Jang, Yu Jin, Tucker, Scott K., Rhee, Catherine, LeBlanc, Lucy, Beck, Samuel, Kim, Jonghwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899959/
https://www.ncbi.nlm.nih.gov/pubmed/29272857
http://dx.doi.org/10.1016/j.scr.2017.12.004