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Advancing Stem Cell Models of Alpha-Synuclein Gene Regulation in Neurodegenerative Disease
Alpha-synuclein (non A4 component of amyloid precursor, SNCA, NM_000345.3) plays a central role in the pathogenesis of Parkinson's disease (PD) and related Lewy body disorders such as Parkinson's disease dementia, Lewy body dementia, and multiple system atrophy. Since its discovery as a di...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900030/ https://www.ncbi.nlm.nih.gov/pubmed/29686602 http://dx.doi.org/10.3389/fnins.2018.00199 |