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Advancing Stem Cell Models of Alpha-Synuclein Gene Regulation in Neurodegenerative Disease

Alpha-synuclein (non A4 component of amyloid precursor, SNCA, NM_000345.3) plays a central role in the pathogenesis of Parkinson's disease (PD) and related Lewy body disorders such as Parkinson's disease dementia, Lewy body dementia, and multiple system atrophy. Since its discovery as a di...

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Detalles Bibliográficos
Autores principales: Piper, Desiree A., Sastre, Danuta, Schüle, Birgitt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900030/
https://www.ncbi.nlm.nih.gov/pubmed/29686602
http://dx.doi.org/10.3389/fnins.2018.00199